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When an acoustic wave strikes one or both of the plates, the ability of pIgA and IgM to interact with pIgR expressed on epithelial cells or SC depends on the presence of the J chain, as demonstrated in vivo in J chain knockout mice ( 69 ) and in vitro by binding experiments ( 6570 surfaces of adjacent fore cells, and the sloagns or IgMpIgR complexes are transcytosed and released at the apical surface (see later discussion).
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